Compounded GLP-1s with a certificate of analysis available on request
Rating reflects Yucca Health's public Trustpilot TrustScore of 4.6 across 1,217 reviews at the time of review, not an independent survey by this site.
Yucca Health is a telehealth platform connecting patients with licensed providers and pharmacies for compounded GLP-1 treatment, with semaglutide from $125 per month on a six-month plan and tirzepatide from $225. Its most distinctive feature is that it offers a certificate of analysis on request — third-party documentation of what is actually in the vial, which very few compounded programs volunteer. Free two-day expedited shipping is included, and it carries a solid public review score.
We recommend CoreAge Rx as our top choice for GLP-1 weight loss programs. With a 4.9/5 rating from 12,848 reviews, they offer personalized care, dedicated health coaching, and exceptional results.
* This is a sponsored recommendation. See our affiliate disclosure for details.
Complete the online assessment covering your health history and goals
A licensed provider reviews your responses and determines eligibility
Choose a plan — month-to-month at $146, or six months at $125/month for semaglutide
Your prescription is fulfilled by a state-licensed pharmacy
Request a certificate of analysis if you want documentation of the formulation
Medication ships with free expedited two-day delivery
Documentation of the compounded product's composition, available to patients who ask — a transparency step most compounded programs do not offer.
Fast shipping is included rather than being an upsell, which matters for a temperature-sensitive medication.
Compounded semaglutide and compounded tirzepatide are both available.
Care team, treatment details, and progress live in one place rather than being spread across email.
At $146/month for semaglutide, you can start without a long prepaid commitment, with $125/month on the six-month plan.
Yucca supports other health needs beyond weight management, so care can consolidate on one platform.
4.6
1,217 reviews
Priscilla N.Verified User
Tulsa, OK
I asked what was actually in the vial and they sent documentation without pushing back. After reading about compounding I wanted that, and nobody else I contacted would provide it.
Grant L.Verified User
Colorado Springs, CO
Medication arrived cold and on time both refills. For something that has to stay refrigerated, expedited shipping being standard rather than an upcharge is the right call.
Aisha D.Verified User
Newark, NJ
I didn't want to prepay six months before knowing how I'd tolerate it. $146 month-to-month is reasonable and I moved to the longer plan after two months.
Tim R.Verified User
Rochester, NY
Nothing on the site said whether my cost changes at higher doses so I had to email. Answer was fine but it should be published. Otherwise the service has been solid.
Lorna K.Verified User
Savannah, GA
Care team messages, my dose schedule, and shipment tracking are all in the portal. Small thing but it beats digging through email for what dose I'm supposed to be on.
Other GLP-1 providers worth comparing before you commit.
Clover Meds
Lower pricing, flat across all doses, with published exclusion criteria.
Embody
Lower entry price at $79/month with documented HSA/FSA acceptance.
Claya
Names its partner pharmacies publicly and includes lab services in the subscription.
Fridays
Adds a brand-name pathway and a deeper included support stack.
Our category rankings, head-to-head comparisons, and the guides worth reading before you decide.
Semaglutide plans start at $125 per month on the six-month plan ($750 total), with month-to-month at $146 per month. Tirzepatide is advertised from $225 per month.
It is documentation of what a batch of medication actually contains. Because compounded drugs are not FDA-reviewed, being able to request this documentation is a meaningful transparency step — most compounded programs do not offer it.
No. Yucca offers compounded semaglutide and tirzepatide prepared by state-licensed pharmacies. Compounded formulations are not FDA-approved and clinical trial data for brand-name products does not apply to them.
Yucca does not state a flat-price-across-doses policy publicly. Ask what your cost becomes at your maintenance dose before enrolling, since dose-tiered pricing is common in compounded programs.
Yucca includes free expedited two-day shipping.
No. Yucca states no insurance is required, and compounded medication is not covered by insurance regardless of provider.
Date reviewed: August 2026
Sources
Medical disclaimer: This review is informational and is not medical advice or an endorsement. Pricing, medication availability, and program terms change frequently — verify current details directly with the provider before enrolling. Compounded medications are not FDA-approved. Only a licensed clinician who knows your medical history can determine whether a GLP-1 medication is appropriate for you.
Program Subscription
From $125/month (semaglutide, 6-month plan)
Medication Cost
Included in the plan price
Insurance
Not accepted; no insurance required
Disclosure: We may receive compensation when you click links to Yucca Health. See our affiliate disclosure for details.
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